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Sep 5, 2018 · Since T-bet contributes to maintain suppressive function of Tregs 30,31, we then assessed functional difference between these two subsets of Tregs. First, we determined their potential to Th1 ...Jul 24, 2015 · For example, whereas T-bet is expressed by, and has a functional role in the formation of, terminally differentiated CD8 + T cells in acute infection 1,127, during chronic infection T-bet controls ...

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Product Specific Information. Description: The eBio4B10 monoclonal antibody reacts with mouse and human T-bet. T-bet is a Th1-specific T-box transcription factor critical to the development of the Th1 CD4+ T cell lineage. This is known based on the observations that T-Bet deficient mice have impaired Th1 cell development, and that ectopic ...

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